NAP3: Major Complications of Central Neuraxial Block in the United Kingdom

What is NAP3?

Central neuraxial blocks (CNB) involve the injection of pain-relieving drugs into the spinal canal. CNB has the potential to provide patients with optimal pain relief, but can also lead to patient harm.

The number of CNB performed in the UK was previously unknown, as was the frequency with which CNB leads to harm to the patients.

NAP3 was designed to answer the questions:

  • What types of CNB are used in the UK, and how often?
  • How often do major complications, leading to permanent harm, occur in association with CNB?
  • What happens to the patients experiencing these complications?

What were the findings?

Please click below to download the sections of the NAP3 Report.

Executive Summary  CSQ-NAP3-ES.pdf (291 KB)
Introductions  CSQ-NAP3-Intros.pdf (989 KB)
Section 1  CSQ-NAP3-Section1_0.pdf (1.15 MB)
Section 2  CSQ-NAP3-Section2.pdf (2.88 MB)
Section 3  CSQ-NAP3-Section3.pdf (469 KB)

Further Reading

Presentation on NAP3 Results
Dr Tim Cook - Royal United Hospital, Bath

Article on NAP3 App in RCoA Bulletin

Report on NAP3 in the British Journal of Anaesthesia